Tobacco 'could help treat cancer'
MIL/BBC News, Jul 24, 2008. Author:
July 24, 2008 - The tobacco plant - responsible for millions of cancer cases - may actually offer the means to treat one form of the disease, a study suggests.
US scientists used the plant to "grow" key components of a cancer vaccine.
The National Academy of Sciences study suggests they could be used to tackle a form of lymphoma.
UK specialists said while "potentially exciting", more research would be needed to test how well the vaccine actually worked.
The ironic new role for tobacco is the work of researchers from Stanford University in California.
They are using the plants as factories for an antibody chemical specific to the cells which cause follicular B-cell lymphoma, a type of non-Hodgkin's lymphoma.
These antibodies are put into a patient newly-diagnosed with the disease, to "prime" the body's immune system to attack any cell carrying them.
If successful, this would mean the body would then recognise and destroy the lymphoma cells.
However, every patient's antibodies are different, and would need to be produced quickly once the diagnosis was made.
The idea is not a new one - attempts have already been made to grow these antibodies inside animal cells, with mixed success.
However, a plant-grown vaccine would be much cheaper and in theory could carry less risk to the patient, as animal cells might hold unknown viruses.
So far, the experimental vaccine has only been tested on a handful of patients to check for any side-effects of using plant-produced antibodies, so its effectiveness at fighting the disease is uncertain.
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